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Toxicogenomics in Predictive Carcinogenicity (Issues in Toxicology)

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[PDF.jn78] Toxicogenomics in Predictive Carcinogenicity (Issues in Toxicology)

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 | #6735471 in Books |  2016-07-26 | Original language:English | PDF # 1 |  9.30 x1.30 x6.40l,.0 | File type: PDF | 524 pages

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Research over the past decade has demonstrated that TGx methods of various types can be used to discriminate modes of mutagenesis as a function of dose. TGx can quickly inform safety evaluation regarding potential mechanisms of conventional outcomes and can provide essential dose-response information. This can then be used to ascertain the sequence of key events in a putative mode of action as may apply in quantitative cancer risk assessment. With the increasing compl...

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