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Oligonucleotide Synthesis: Methods and Applications (Methods in Molecular Biology)

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 | #3763298 in Books |  Humana Press |  2004-09-01 | Original language:English | PDF # 1 |  9.21 x1.00 x6.14l,1.87 | File type: PDF | 436 pages

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A collection of powerful new techniques for oligonucleotide synthesis and for the use of modified oligonucleotides in biotechnology. Among the protocol highlights are a novel two-step process that yields a high purity, less costly, DNA, the synthesis of phosphorothioates using new sulfur transfer agents, the synthesis of LNA, peptide conjugation methods to improve cellular delivery and cell-specific targeting, and triple helix formation. The applications include using mo...

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